Redox-Active Molecules as Therapeutic Agents
Material type:
TextLanguage: English Publication details: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022Description: 1 online resource (266 p.)Content type: - text
- computer
- online resource
- 9783036543819
- 9783036543826
- books978-3-0365-4382-6
- Biology, life sciences
- Research and information: general
- (poly)phenols
- adipose-derived mesenchymal stem cell
- amniotic membrane-derived mesenchymal stem cell
- antioxidant capacity
- antioxidants
- apoptosis
- apurinic/apyrimidinic endonuclease 1
- assisted reproductive technology
- ATF4
- BAPN
- bioactivity-based assays
- breast cancer
- cancer therapy
- cardiorenal syndrome
- carnosic acid
- CD IGS rats
- cell cycle
- cell invasion
- chemoresistance
- cisplatin
- conditioned medium
- curcumin
- cyanidin
- Cysteamine
- cytotoxicity
- DNA damage
- doxorubicin
- E3330
- embryo
- EMT
- glutathione peroxidase
- glutathione reductase
- GSH
- H2S donors
- hydrogen sulfide
- hypercholesterolemia
- in vitro culture
- in vitro fertilization
- inhibitors
- invasion
- KEAP1
- lactic acid bacteria
- lysyl-oxidase
- lysyl-oxidase like 2
- metabolomics
- metastases
- migration
- mitochondrial reactive oxygen species
- N-acetyl cysteine
- n/a
- non-small cell lung cancer
- NRF2
- nuclear factor erythroid 2-related factor 2 (Nrf2)
- oxidative stress
- OxPhos
- peroxiredoxin 3
- pro-oxidant therapy
- prostate cancer
- reactive oxygen species
- redox signaling
- Rubus genus
- selenium-enriched Enterococcus faecium
- selenium-enriched Streptococcus thermophilus
- SGK1
- sildenafil
- systemic sclerosis
- thiostrepton
- thiosulfate
- verbascoside
- withanolide
- yeast-based discovery platform
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Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of research by providing novel mechanistic insights. This book compiles a collection of 13 articles, covering a range of topics from in vitro studies to clinical research, focused on the potential therapeutic effects of either natural or synthetic compounds, applicable to different redox-related diseases.
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