Solid Dispersions for Drug Delivery Applications and Preparation Methods
Material type:
TextLanguage: English Publication details: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022Description: 1 online resource (243 p.)Content type: - text
- computer
- online resource
- 9783036526386
- 9783036526393
- books978-3-0365-2638-6
- Manufacturing industries
- Medicine and Nursing
- absorption
- absorption modeling
- acalabrutinib
- acid reducing agent
- acid-reducing agent
- amorphous
- amorphous solid dispersion
- antichagasic activity
- bioavailability
- bioavailability enhancement
- biological applications
- coamorphous
- cocrystals
- core-sheath nanofibers
- crystallinity
- delivery system
- dissolution
- drug delivery
- drug-rich phase
- dry powder inhalers
- ex vivo drug permeation
- ex vivo permeation
- factorial design
- fexofenadine hydrochloride
- GastroPlus
- green nanotechnology
- hydrogen bonding
- hydrophobic drug
- hydrophobicity
- ibuprofen
- in silico prediction
- in vivo pharmacokinetic studies
- kinase inhibitor
- liquid-liquid phase separation
- n/a
- nanoemulsion
- nanosuspension
- oral fast dissolving film
- paroxetine
- PEG 20,000
- permeability enhancement
- pH effect
- poloxamer188
- poly(2-oxazolines)
- poly(N-vinyl pyrrolidone)
- polymeric carriers
- proton pump inhibitor
- pulmonary drug delivery
- raloxifene
- rapid release
- response surface methodology
- solid dispersion
- solid dispersions
- solubility
- spray drying
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Since their first application in the improvement of solubility of orally delivered drugs, applications of solid dispersions have considerably expanded to include cancer, infections, and inflammatory conditions. This book presents recent advancements in the development and use of solid dispersions for different therapeutic applications. This book can be particularly useful for researchers as well as postgraduate students in formulation sciences and drug delivery. Undergraduate students will also find elements of this book very relevant to scientific fundamentals such as solubility and crystallization of amorphous materials as well as drug delivery challenges.
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