Osteoarthritis: From Molecular Pathways to Therapeutic Advances
Material type:
TextLanguage: English Publication details: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022Description: 1 online resource (306 p.)Content type: - text
- computer
- online resource
- 9783036534633
- 9783036534640
- books978-3-0365-3463-3
- Biology, life sciences
- Research and information: general
- adipokines
- aging
- angiogenesis
- autophagy
- biomarker
- cartilage
- cartilage trauma
- celecoxib
- cell death
- chemokines
- chondrocyte
- chondrocytes
- chondrocytic commitment
- chondroitin
- chondroprotection
- collagen
- cytokines
- dietary supplements
- early diagnosis
- ECM
- exercise
- glucosamine
- glucosamine sulfate
- hexosamine biosynthetic pathway
- hyaluronic acid
- hydrostatic pressure
- hypertrophy
- IFNγ, IL-17
- IL-1β
- IL-4
- inflammaging
- inflammation
- infrared spectroscopy
- inhibitor
- Interleukin-1β
- joint modelling
- linker modifications
- matrix metalloproteinases
- mechanical loading
- meniscus
- mesenchimal stem cells
- methylsulfonylmethane
- microRNA
- miRNAs
- mitochondrial dysfunction
- MMP-13
- molecules
- MRM
- native tissue analysis
- near-infrared spectroscopy
- NF-κB
- NO synthase
- nutraceuticals
- O-GlcNAcylation
- obesity
- osteoarthritis
- osteochondral explant culture
- oxidative stress
- pathogenesis
- pharmacological assay
- physical activity
- post-traumatic osteoarthritis
- proteomics
- Raman spectroscopy
- regulation
- remodeling
- RNA-Seq
- sex as a biological variable
- SMAD2/3 signaling
- TGF-β
- therapy
- type II collagen
- vibrational spectroscopy
- visfatin
- vitamin C
- vitamin D
- whole transcriptome sequencing
- Wnt/β-catenin
Open Access Unrestricted online access star
In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.
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English
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